Verified Customer
Jeff R., 55
I'm fairly new to this but I've already noticed some gains in muscle development.
Rating: 5 out of 5
Monthly Supply (9mg)
Growth Hormone Releasing Peptide
Support deeper sleep, faster recovery, and leaner muscle. All from your own growth hormone.
20% Off Rythm Blood Test
Injection supplies included
2-day temp-controlled shipping
Ongoing support from a real care team
The decline is quiet at first
Growth hormone drops about 15% every decade after your mid-20s. You feel it before you can name it.
You haven't changed your workouts or what you eat, but your body composition is. More fat around the middle, less muscle than there used to be.
Leg day used to cost you a day. Now it's closer to three, and you're not training harder than you used to be.
You can fall asleep fine. It's the 2am wake-up and the next-day fog that's become the pattern.
You've probably written it off as stress or age. That's possible. But it might also be your pituitary.
What's actually happening
This isn't just "getting older"
After your mid-20s, your pituitary gland produces less growth hormone every year. By your 40s, daily GH output can be a fraction of what it was at 25. The symptoms are familiar: worse sleep, slower recovery, more body fat, less drive.
Your pituitary still works, though. It just needs the right input. Sermorelin is a synthetic version of the signal your hypothalamus sends to trigger a GH release. It works with your body's natural rhythm rather than bypassing it with a fixed synthetic dose.
Because sermorelin works through your own pituitary, your body's feedback systems stay intact. In clinical studies, IGF-1 levels have been shown to respond within the first few weeks, and many clients notice sleep improving first, followed by recovery, then body composition over time.
Most growth hormone options are a mess
OTC "HGH Boosters"
They're mostly amino acid blends at doses too small to do anything meaningful. They won't hurt you, but there's no solid evidence that any of them raise GH output in adults.
Synthetic HGH injections
HGH works, but it's expensive, heavily regulated, and replaces what your body should be making on its own. Long-term use can suppress your natural production. Sermorelin signals your pituitary to produce more GH in your body's own rhythm, with your feedback system still intact.
Unregulated Online Sellers
Peptides blew up on TikTok, and so did sellers cutting corners on quality. Many of them operate with no clinician involvement, no sterility testing, and no clear supply chain. The savings disappear if the product doesn't do what it claims.
A Better Option
Why is System better?
For years, the only choices were weak supplements, $500-a-month HGH programs, or gray-market peptides nobody could vouch for. We built System to be the fourth option.
Every order is reviewed by a licensed clinician and compounded by a U.S.-licensed pharmacy. We test every batch independently so you know exactly what's in the vial. And whether you prefer a subcutaneous injection or an oral dissolving tablet, there's a format that works for your life.
Lab tested before it ships
The compound is at the dose stated on the label
Here's what actually separates your options.
System Labs Sermorelin
- Independent third-party lab testing on every batch, with published results for potency, sterility, pH, and endotoxicity
- Both injection and oral dissolving tablet available
- Licensed clinician reviews your case before you receive anything, and stays available throughout
- Compounded by a named, licensed U.S. pharmacy
- First month at $109, no clinic markups, no per-visit fees, no contracts
- Pause or cancel anytime
Compared to
Other growth hormone support options
- Testing happens at the pharmacy level but results are rarely published or accessible
- Most offer injection only or ODT only, not both
- Clinician access varies. Some are review-only with no ongoing contact
- Pharmacy sourcing often unspecified
- Similar pricing can include hidden consultation fees or membership charges
- Cancellation policies vary and are not always clearly stated
Backed by physicians who've trained at the top programs in the country
Dr. Marc Gruner
System Medical Advisor
Sports medicine physician trained at Mayo Clinic in ultrasound and regenerative medicine.
Mayo Clinic
System Laboratories, Inc. Medical Board
01
Dr. Jonathan Hinds
System Medical Advisor
Board-certified in Emergency Medicine. Licensed in all 50 states. Trained at Rutgers University.
Rutgers UniversitySystem Laboratories, Inc. Medical Board
02
Dr. Gregory Tennant
System Medical Advisor
System Medical Advisor Fellowship-trained orthopedic trauma surgeon. Trained at Vanderbilt University.
Vanderbilt UniversitySystem Laboratories, Inc. Medical Board
03
01
Quick intake form
Covers your health history and what you're looking to address. You can fill it out from your phone in a few minutes, no appointment or waiting room involved.
02
Clinician reviews your info
A real licensed provider goes through your intake and reaches out by chat. If you're a good fit they'll let you know. If you're not, they'll tell you that too.
03
Ships straight to your door
Compounded at a certified U.S. pharmacy and shipped in two days with temperature control. Everything you need to get started comes in the box.
Verified Customer
Peter S., 43
My experience with System Labs has been wonderful. I've noticed real benefits and can't wait to continue seeing progress.
Rating: 5 out of 5
Verified Customer
Michael W., 58
It's only been about a month but the most noticeable change has been sleep quality. Solid sleep every night.
Rating: 5 out of 5
Verified Customer
Aubrey E., 46
So far so good. My order arrived quickly and the customer service has been great.
Rating: 5 out of 5
Verified Customer
Michael L., 45
Everything from start to finish has been a great experience. The support I received was excellent and I plan to continue with my treatments.
Rating: 5 out of 5
Verified Customer
Peter J., 39
Quality products with medical supervision. I've noticed a real difference with the products and I'm looking forward to long-term results.
Rating: 5 out of 5
Verified Customer
Cory M., 37
The process was smooth and streamlined. I was impressed by how quickly the clinician responded to my questions, including ones about medication interactions. Everything arrived well-packaged and on time.
Rating: 5 out of 5
Recovery naturally declines after 30
GH production declines after 30, and as pituitary signaling weakens, recovery slows and gains come harder.1 Sermorelin may prompt the pituitary to release GH in its natural pulsed rhythm, supporting repair without overriding the body's feedback loops.2
Recovery signals can drop by up to 45% by the age of 60.
45%
What sermorelin may supports
Sleep
Most clients notice deeper, more restorative sleep within the first few weeks. It tends to be the first thing that shifts.
Recovery
Clients often find they bounce back from training faster and can push harder without the same breakdown the next day.
Muscle
May help support lean mass when paired with consistent training over time.
Composition
Over months of use, can support a shift toward less fat and more muscle, even when the scale doesn't move much.
Vitality
Drive, focus, and afternoon energy that doesn't disappear by 2pm. Clients tend to notice this before anything else changes visibly.
Longevity
Supports the hormonal environment associated with healthy aging and long-term physical performance.
Results come in stages. Here's what the first six months look like.
weeks 1—2
Sleep starts shifting
You'll notice it at night first. Falling asleep faster. Deeper sleep. Some people get vivid dreams. Most don't feel much else yet, and that's completely normal. Your IGF-1 is already rising in the background. The first changes tend to be subtle.
weeks 3—4
Daytime energy comes back
Better sleep starts showing up in your day. The 2pm crash gets smaller. Mood lifts. Some clients feel a steadier baseline energy that they'd forgotten was possible.
month 2
Recovery Returns
Workouts hurt less the next day. You can train harder, more often, without the same breakdown. This is the effect most clients describe as "I feel like myself again at the gym."
Month 3
the body changes
Clothes fit differently. Midsection gets tighter. Muscles look fuller. The scale may not move much because you're trading fat for lean mass at the same time. The mirror and how your clothes fit are better measures than the scale.
Month 4—6
people start to notice
Body composition keeps improving. Skin and hair quality often follow. Energy and drive are at a new baseline. This is when clients stop questioning whether it's working and start asking what comes next.
Transparent Monthly Pricing
Clinical-grade sermorelin, in the format that works for you. No clinic markups. No surprise fees.
Monthly Supply (9mg)
In stock via System Labs
20% Off Rythm Blood Test
Injection supplies included
2-day temp-controlled shipping
Ongoing support from a real care team
Synthetic HGH programs run $500 to $1,500 per month. System Labs Sermorelin starts at a fraction of the price.
No waiting roomsNo per-visit feesNo clinic markups
Pause or cancel anytime
Secure clinician review
Automatic refills aligned with your schedule
Is sermorelin right for you?
This is right for your if
- You're 35 or older and no you're noticing the classic signs of GH decline
- You want better sleep, faster recovery, and a leaner body over time
- You'd rather support your body's own hormone production than replace it
- You want a licensed clinician in the loop, not a guess from a forum
...
This isn't right for you if
- You’ve had cancer in the last 5 years
- You’re pregnant or breastfeeding
- You have untreated thyroid disease
- You're under 25 (GH levels are still naturally high)
Frequently Asked Questions
See if you qualifyHGH injects finished growth hormone directly into your bloodstream, bypassing your pituitary entirely. Sermorelin signals your pituitary to produce more on its own, keeping your body's natural rhythm and feedback systems intact. Long-term synthetic HGH use can suppress your body's own production over time. Sermorelin is designed to work with your system rather than around it, and it costs a fraction of what HGH programs run.
The injection delivers a precise subcutaneous dose and tends to work a little faster. The oral dissolving tablet goes under your tongue and is easier to manage day-to-day since you don't need to handle needles or keep a syringe in the fridge. Both contain clinical-grade sermorelin from the same U.S. pharmacies. Your clinician will help you decide which format makes more sense for you.
Many clients notice a body composition shift over 3 to 6 months. The scale often doesn't move much because fat and lean mass may be shifting at the same time. The mirror and how your clothes fit tend to be better measures than the number on the scale. Individual results vary.
That's accurate and normal for many people. Sleep tends to shift in weeks 1 to 2. Energy and recovery often follow in weeks 3 to 8. Body composition changes may start around month 3. The early changes tend to be subtle, but things typically pick up from there.
Once a day, at night, 30 to 60 minutes before bed. Most clients run 5 nights on, 2 nights off to keep receptor sensitivity high. Your clinician will set your specific protocol.
No. The needle is very small and goes just under the skin, not into muscle. Most clients describe it as a pinprick or nothing at all, and it gets easier after the first few times.
Lower abdomen, outer thigh, or flank. We send a full guide with your order. Rotating sites each night helps keep injection-site reactions minimal.
Most are mild and temporary during the first few weeks: vivid dreams, mild redness at the injection site, occasional headache, or slight water retention in the hands and feet. Your clinician monitors your response throughout and is available if anything comes up.
Many clients use sermorelin alongside testosterone replacement therapy since it works on a different hormonal axis. Your clinician will review your full health picture and let you know whether it makes sense for your situation.
Keep it in the refrigerator. We ship in temp-controlled packaging with a 2-day delivery window so it arrives cold.
First month is $109. After that, $219 per month. Free 2-day shipping on every order. You can pause or cancel at any time with no cancellation fees.
System Mission
Why we built System
The men we know who wanted to do something about this were stuck. HGH programs that cost a fortune, peptides from websites nobody could actually vouch for, or supplements that didn't do much of anything. When they brought it up with their doctor, most of them got referred to a specialist with a six-month wait.
We figured there had to be a better way to do this. A pharmacy we can name. Lab testing we can show you. A clinician you can actually reach. Pricing that doesn't assume you'll quit after a month. That's System. Sermorelin is where we started and more is coming.